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RamirezMD

Jelly Bean

"Manage any volumetric pump like a TCI device with different intravenous drugs"

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iTIVA is a simulation program that provides information about distribution of drugs based on mathematical models, and it simulate the behavior of a TCI pump, obtaining infusion rates to reach and maintain a stable target effect site concentration, those schemes can be implemented in volumetric infusion pumps, and be guided with pharmacokinetics models.

So now pharmacokinetics can become an easy topic and understanding what is going on during a infusion of a intravenous drug, too.

Pharmacokinetic models

iTIVA has 11 drugs y 33 pharmacokinetic models, that are updated continuously:

-Remifentanil

	Adults: Minto , Eleveld, Kim	

	Kids: Rigby-Jones, Ross

-Fentanyl 	

	Adults: Shafer, Scott 	

	Kids: Ginsberg, Encinas (Neonates)

-Sufentanil 	

	Adults: Gepts, Bovill 	

	Kids: Greely

-Alfentanil 	

	Adults: Maitre

-Ketamine	

	Adults: Domino, Clements-250

 	Kids: Herd, Elkomy

-Procaine

	Adults: Seifen

-Lidocaine 

	Adults: Dyck, Schnider

-Propofol 

	Adults: Schnider, Eleveld, Marsh, Cortinez

 	Kids: Peadfusor, Kataria, Eleveld

-Dexmedetomidine

 	Adults: Hannivoort, Dyck, Lin, Venn 

	Kids: Potts

-Midazolam 

	Adults: Albrecht, Greenblatt

-Tranexamic 

	Adults: Grassin-Delyle

	Kids: Goobie, Grassun-Delyle

iTIVA also calculate the end tidal (Et) for Isoflurane, Sevoflurane, Desflurane for the MAC age, with the use of the Mapleson equation.

Created by David Ramirez MD, Cali - Colombia. Universidad de Valle. david@itiva.co

• WARNING:

iTIVA is not designed to handle intravenous drugs for individual patients. Its use is limited to educational purposes to demonstrate pharmacokinetic principles when performing intravenous anesthesia. Therefore the user assumes all risks from the use of this application for clinical purposes. 

Infusion schemes are obtained from concentrations based on models published in the medical literature; therefore concentrations achieved from these schemes can vary widely, in the same manner for clinical effects.

This application should only be used by people with extensive knowledge in Anesthesiology.

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